Phase
Condition
Esophageal Cancer
Treatment
SDD
Clinical Study ID
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Diagnosis of primary esophageal adenocarcinoma or squamous cell carcinoma (cT1b-4a,N0-3,M0) in the mid or distal esophagus or at the level of thegastro-esophageal junction scheduled for undergoing transthoracic esophagectomy withcurative intent or for esophageal reconstruction with a gastric or jejunalinterposition
Age ≥ 18 years,
Able to give written informed consent.
Exclusion
Exclusion Criteria:
Patients planned for rescue surgery,
Patients planned for colonic interposition,
Known or suspected pregnancy,
Patients who have undergone upper GI surgery within 30 days before randomization,
Unable to understand the study information, study instructions and give informedconsent.
Patients enrolled in a trial that would interact with the intervention
Patients with a known allergy, sensitivity, or interaction to investigationalmedicinal product.
Patients with known/documented colonization of Enterobacteriaceae and or PseudomonasAeruginosa that are resistant to both tobramycin/gentamicin and to carbapenemantibiotics
Patients undergoing CVVH.
Patients with documented chronic renal failure (GFR < 15 mls/min) or who are onchronic intermittent hemo- or peritoneal dialysis,
Women of childbearing potential at risk of pregnancy, not using adequatecontraception,
Patients with the inability to swallow the SDD
Patients with pre-existing degenerative neuromuscular diseases like, but not limitedto, myasthenia gravis or Parkinson disease).
Study Design
Study Description
Connect with a study center
UZ Leuven
Leuven, 3000
BelgiumActive - Recruiting
Radboudumc
Nijmegen, 6525GA
NetherlandsActive - Recruiting
Not the study for you?
Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.