Last updated: May 6, 2023
Sponsor: First Affiliated Hospital, Sun Yat-Sen University
Overall Status: Active - Recruiting
Phase
3
Condition
Carcinoma
Nasopharyngeal Cancer
Treatment
3 cycles induction chemotherapy
2 cycles induction chemotherapy
Clinical Study ID
NCT05860868
Two VS Three
Ages 18-65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Age 18-65 years old;
- Pathologically confirmed non-keratinizing nasopharyngeal carcinoma;
- Stage T3-4N0-1 (according to the UICC/AJCC 8th);
- No distant metastasis;
- Have not received anti-cancer treatment in the past;
- ECOG (Eastern Cooperative Oncology Group of the United States): 0-1;
- Adequate hematologic, hepatic and renal function.
Exclusion
Exclusion Criteria:
- The purpose of treatment is palliative;
- Diagnosed with other malignant tumors at the same time;
- Malignant tumor history;
- Pregnancy or breastfeeding, or expect to become pregnant during the clinical trialperiod;
- Combined serious illness.
Study Design
Total Participants: 474
Treatment Group(s): 2
Primary Treatment: 3 cycles induction chemotherapy
Phase: 3
Study Start date:
May 01, 2023
Estimated Completion Date:
May 31, 2030
Connect with a study center
First Affiliated Hospital, Sun Yat-Sen University
Guangzhou, Other (Non U.s.) 510080
ChinaActive - Recruiting

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