The Efficacy of Speech Competition Training on Auditory Hallucination in Schizophrenia

Last updated: July 4, 2023
Sponsor: Jing SHI
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mood Disorders

Tourette's Syndrome

Tinnitus

Treatment

the soothing music

speech competition training

Clinical Study ID

NCT05850923
AH-IA-2021
  • Ages 18-55
  • All Genders

Study Summary

One hundred schizophrenia patients with auditory hallucinations will be recruited and randomized into group A and group B. Participants of group A will firstly receive a speech competition training for 2 weeks, and those in group B will firstly receive music intervention as placebo treatment. Specifically, speech competition training include voice competition training twice a day in adjunction with drug treatment, and the patients will be required to perform voice-related tasks according to the instruction. The reaction time, accuracy rate and the number of auditory hallucinations during the task will be recorded. On the other hand, the placebo treatment includes soothing music twice a day for a fixed period of time while patients receiving drug treatment. After 2 weeks, the interventions for group A and group B will be switch.

Clinical symptoms will be evaluated using the auditory hallucinations rating scale, positive and negative syndrome scale, belief about voices questionnaire-revised at baseline, 2-week follow up and 4-week follow up. All the data will be analyzed with the Statistical Product and Service Solutions(SPSS) software.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Fulfilling the diagnostic criteria for schizophrenia as in the InternationalClassification of Diseases (ICD) - 10;
  • Aged 18-55 years old;
  • Education level over 6 years;
  • The score of P3 item in PANSS ≥ 3 points;
  • Taking antipsychotics at a therapeutic dose for at least 1 month, and the symptoms ofauditory hallucinations have not been significantly improved, and the score ofAuditory Hallucinations Rating Scale (AHRS) is still greater than 18 points;
  • Capable of understanding and singing a written informed consent form, and be able tocooperate in completing intervention training and assessments.

Exclusion

Exclusion Criteria:

  • Diagnosing other Axis I mental disorders;
  • A history of severe neurological disease, brain trauma, major physical disease orhistory of drug dependence;
  • Auditory hallucinations caused by organic brain diseases;
  • Patients who cannot cooperate with the completion of training;
  • Patients with serious suicidal or self injurious behavior;
  • Pregnant and lactating women;
  • History of alcohol abuse;
  • Intellectual impairment (IQ<70);
  • Patients with hearing impairment.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: the soothing music
Phase:
Study Start date:
November 15, 2022
Estimated Completion Date:
June 30, 2024

Connect with a study center

  • Shanghai Mental Health Center

    Shanghai, 200030
    China

    Active - Recruiting

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