Treatment Strategies for Unruptured Intracranial Aneurysms in the Chinese Population China Treatment Trial for Unruptured Intracranial Aneurysm (ChTUIA)

Last updated: March 30, 2025
Sponsor: Beijing Tiantan Hospital
Overall Status: Completed

Phase

N/A

Condition

Aneurysm

Treatment

observation

Clinical Study ID

NCT05844163
KY2022-226
  • Ages > 18
  • All Genders

Study Summary

The goal of this prospective observational cohort study is to learn about treatment strategies for unruptured intracranial aneurysms in the Chinese population. The main questions it aims to answer are:

  • To establish a cohort of patients with intracranial unruptured aneurysm and explore the optimal clinical treatment strategy.

  • To establish clinical management path for patients with unruptured intracranial aneurysm.

According to the treatment of all patients with unruptured intracranial aneurysm, they were divided into the following groups: 1. Conservative treatment group; 2. Intracranial aneurysm clipping group; 3. Coil embolization or stent-assisted coil embolization group; 4. Flow diversion group.

Eligibility Criteria

Inclusion

Inclusion Criteria:

A. age > 18 years. B. at least one intracranial aneurysm needs to be treated by craniotomy, endovascular treatment or combined surgery.

C. patients' consent were obtained.

Exclusion

Exclusion Criteria:

  1. Ruptured intracranial aneurysms, accompanied by subarachnoid hemorrhage or cerebralhemorrhage ;

  2. Traumatic, infectious and atrial myxoma-associated intracranial aneurysms ;

  3. Combined with cerebrovascular malformations;

  4. Combined with brain tumors or malignant tumors in other parts ;

  5. Combined with systemic connective tissue disease and systemic rheumatic disease ;

  6. Due to other diseases, or poor general condition, the expected survival time is notmore than 12 months ;

  7. During pregnancy and perinatal period.

Study Design

Total Participants: 31595
Treatment Group(s): 1
Primary Treatment: observation
Phase:
Study Start date:
December 01, 2021
Estimated Completion Date:
December 01, 2024

Connect with a study center

  • Capital Medical University Affiliated Beijing Tiantan Hospital

    Beijing, Beijing
    China

    Site Not Available

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