NSAID Use After Robotic Partial Nephrectomy

Inclusion Criteria:

• Patients undergoing uncomplicated robotic assisted laparoscopic partial nephrectomyfor renal mass at the University of Miami Hospital and Network Sites (DeerfieldBeach, Plantation, Lennar (Coral Gables), and Kendal).

• Age 18-99.

• Ability to understand and the willingness to sign a written informed consentdocument.

Exclusion Criteria:

• Allergy to NSAIDs

• Myocardial infarction or unstable angina within 12 months.

• Any history of coronary artery bypass graft surgery.

• History or active peptic ulcer disease, gastrointestinal (GI) bleeding, GIperforation. History of bleeding disorder. Glomerular filtration rate (GFR) < 60mL/min/1.73m2 (Modification of Diet in Renal Disease (MDRD) equation).

• Taking any anti-platelet or anti-coagulation medications concurrently (e.g.warfarin, aspirin, clopidogrel, rivaroxaban etc.)

• Chronic opioid use (use within 12 weeks) or history of opioid use disorder.

• Solitary kidney.

• Pregnancy.

• Inability to give informed consent or unable to meet requirement of the study forany reason.