An Observational Study to Assess Ubrogepant Tablets and Atogepant Tablets to Treat Migraine in Adult Participants

Last updated: April 2, 2026
Sponsor: AbbVie
Overall Status: Completed

Phase

N/A

Condition

Pain (Pediatric)

Headaches

Oral Facial Pain

Treatment

N/A

Clinical Study ID

NCT05827887
P24-078
  • Ages > 18
  • All Genders

Study Summary

Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate how effective the use of ubrogepant and atogepant is in treating adult participants with migraine.

Urogepant (Ubrelvy) and Atogepant (Qulipta) are approved drugs for treatment of migraine in adults in the US. Approximately 200 adult participants who are prescribed Ubrogepant or atogepant by their doctors will be enrolled in this study in Israel.

Participants will receive ubrogepant oral tablets or atogepant oral tablets as prescribed by their physician. Participants will be followed for 90 days.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Confirmed diagnosis of migraine according to the ICHD-3 upon judgement of thetreating physician

  • The patients should be naive to the designated treatment

  • Ability to fill an e-diary app

Exclusion

Exclusion Criteria:

  • Patients who cannot be treated with UBRO or ATO according to the applicable approvedlabel

  • Patients participating in a concurrent clinical interventional study or within thelast 30 days

  • Patients who were previously treated with rimegepant will be excluded from the study

Study Design

Total Participants: 226
Study Start date:
June 25, 2023
Estimated Completion Date:
January 28, 2026

Connect with a study center

  • Edith Wolfson Medical Center /ID# 269740

    Holon, Central District 5822012
    Israel

    Site Not Available

  • Maccabi Healthcare Services /ID# 254171

    Kfar Saba, Central District 4420123
    Israel

    Site Not Available

  • Meir Medical Center /ID# 254170

    Kfar Saba, Central District 4428164
    Israel

    Site Not Available

  • Maccabi Healthcare Services /ID# 254171

    Kfar Saba 294514, Central District 294904 4420123
    Israel

    Site Not Available

  • Meir Medical Center /ID# 254170

    Kfar Saba 294514, Central District 294904 4428164
    Israel

    Site Not Available

  • Soroka University Medical Center /ID# 254551

    Be'er Sheva, HaDarom 8410101
    Israel

    Site Not Available

  • Soroka University Medical Center /ID# 254551

    Beer Sheva, HaDarom 8410101
    Israel

    Site Not Available

  • Shaare Zedek Medical Center /ID# 254169

    Jerusalem, Jerusalem 91031
    Israel

    Site Not Available

  • Shaare Zedek Medical Center /ID# 254169

    Jerusalem 281184, Jerusalem 293198 91031
    Israel

    Site Not Available

  • ZIV Medical Center /ID# 257360

    Safed, Northern District 13100
    Israel

    Site Not Available

  • ZIV Medical Center /ID# 257360

    Safed 293100, Northern District 294824 13100
    Israel

    Site Not Available

  • Assuta Ashdod Medical Center /ID# 260020

    Ashdod, Southern District 7747600
    Israel

    Site Not Available

  • Soroka University Medical Center /ID# 254551

    Beersheba, Southern District 8410101
    Israel

    Site Not Available

  • Assuta Ashdod Medical Center /ID# 260020

    Ashdod 295629, Southern District 294952 7747600
    Israel

    Site Not Available

  • Soroka University Medical Center /ID# 254551

    Beersheba 295530, Southern District 294952 8410101
    Israel

    Site Not Available

  • The Chaim Sheba Medical Center /ID# 254550

    Ramat Gan, Tel Aviv 5265601
    Israel

    Site Not Available

  • Tel Aviv Sourasky Medical Center /ID# 263089

    Tel Aviv, Tel Aviv 6423906
    Israel

    Site Not Available

  • The Chaim Sheba Medical Center /ID# 254550

    Ramat Gan 293788, Tel Aviv 293396 5265601
    Israel

    Site Not Available

  • Tel Aviv Sourasky Medical Center /ID# 263089

    Tel Aviv 293397, Tel Aviv 293396 6423906
    Israel

    Site Not Available

  • Hadassah Medical Center /ID# 257352

    Jerusalem, Yerushalayim 9112001
    Israel

    Active - Recruiting

  • Clalit HMO /ID# 257364

    Gani Tikva, 5591236
    Israel

    Site Not Available

  • Hadassah Medical Center-Hebrew University /ID# 257352

    Jerusalem, 91120
    Israel

    Site Not Available

  • Hadassah Medical Center-Hebrew University /ID# 257352

    Jerusalem 281184, 91120
    Israel

    Site Not Available

  • Ziv Medical Center /ID# 257360

    Safed, 13100
    Israel

    Active - Recruiting

Map preview placeholder

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.