Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block vs Erector Spinae Plane Block in Open Nephrectomy

Last updated: May 16, 2025
Sponsor: Cairo University
Overall Status: Completed

Phase

N/A

Condition

N/A

Treatment

Rhomboid intercostal subserratus plane block

Thoraccic Epidural analgesia

Erector spinae plane block

Clinical Study ID

NCT05822011
Rhomboid block in nephrectomy
  • Ages 18-65
  • All Genders

Study Summary

Our aim is to measure the efficacy of rhomboid intercostal subserratus plane block and erector spinae plane block in patients undergoing open nephrectomy

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Type of surgery; open nephrectomy.

  2. Physical status ASA II, III.

  3. Body mass index (BMI): > 20 kg/ m2 and < 35 kg/ m2.

Exclusion

Exclusion Criteria:

  1. Patient refusal.

  2. Local infection at the puncture site.

  3. Severe respiratory or cardiac disorders.

  4. Advanced liver or kidney disease.

  5. History of psychological disorders and/or chronic pain.

  6. Contraindication to regional anesthesia e.g. local sepsis, pre- existing peripheralneuropathies and coagulopathy.

  7. Patients with known sensitivity or contraindication to amide local anesthetics usedin the study.

Study Design

Total Participants: 42
Treatment Group(s): 3
Primary Treatment: Rhomboid intercostal subserratus plane block
Phase:
Study Start date:
April 20, 2023
Estimated Completion Date:
May 15, 2025

Study Description

Open nephrectomy incision is associated with a high incidence of intense immediate postoperative pain and chronic pain the months following surgery. Regional anesthesia techniques are commonly recommended for pain management in open nephrectomy as they decrease parenteral opioid requirements and improve patient satisfaction. Rhomboid intercostal subserratus plane block (RISS) is considered a novel approach for chest wall and upper abdominal analgesia, initially showed promising results, first reported in 2016. Erector Spinae Plane block (ESB), was initially described in 2016 for analgesia in thoracic neuropathic pain. It has also been widely used in both adults and children at different levels for different indications. Epidural analgesia is the gold standard for perioperative analgesia in open surgery.

Connect with a study center

  • National Cancer Institute

    Cairo,
    Egypt

    Site Not Available

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.