Clinical Study of Umbilical Cord Blood Mononuclear Cell Therapy for the Treatment of Chronic Atrophic Gastritis

Last updated: April 15, 2024
Sponsor: Shandong Provincial Hospital
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Non-ulcer Dyspepsia (Nud)

Heartburn

Bowel Dysfunction

Treatment

Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules

Mononuclear cells

Clinical Study ID

NCT05808010
SWYX:NO.2022-1037
  • Ages 18-65
  • All Genders

Study Summary

To evaluate the efficacy and safety of umbilical cord blood mononuclear cells in the treatment of chronic atrophic gastritis.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Subjects voluntarily participated in the study and signed an informed consent.
  2. The age is 18-65 years old, regardless of gender.
  3. Patients with chronic atrophic gastritis by gastroscopy and pathological examination.
  4. Patients with a negative C13 breath test or have eradicated Helicobacter pyloriinfection.
  5. Patients without contraindications to submucosal injection of umbilical cord bloodderived mononuclear cells.

Exclusion

Exclusion Criteria:

  1. Patients with gastric ulcer, erosive gastritis, active upper gastrointestinalbleeding, gastric varices, or other gastric tumors.
  2. Patients who are taking or have taken proton pump inhibitors, antibiotics,glucocorticoids, nonsteroidal anti-inflammatory drugs and immunosuppressants in thelast six months.
  3. People who have had gastric surgery or required gastric surgery during the study.
  4. Patients with severe systemic diseases (diseases of cardiovascular, liver, blood,kidneys, lungs or liver).
  5. Pregnant or nursing females.
  6. Patients who are reluctant to accept endoscopy and treatment.

Study Design

Total Participants: 60
Treatment Group(s): 2
Primary Treatment: Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
Phase:
Study Start date:
June 07, 2023
Estimated Completion Date:
April 30, 2026

Connect with a study center

  • Shandong Provincial Hospital

    Jinan, Shandong 250021
    China

    Site Not Available

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