A Study of Magnesium and Bladder Spasms Following Ambulatory Urologic Procedures

Inclusion Criteria:

• Be undergoing a bladder invasive procedure with or without planned urinary catheteron Mayo Clinic Gonda 7 Outpatient Procedure Center.

Exclusion Criteria:

• Are unable to grant informed consent or comply with study procedure.

• Allergy or known sensitivity to magnesium or Renacidin.

• Expected or high risk of bladder extravasation.

• Ongoing atrial fibrillation prior to surgery.

• Are undergoing emergency surgery.

• Are pregnant.

• Known hypermagnesemia.

• Patients with neuromuscular weakness (e.g., Myasthenia gravis) due to magnesium'smuscle weakening effect.

• Patients with myocardial compromise or cardiac conduction defects because ofmagnesium's anti-inotropic effects.

• Patients with renal insufficiency, glomerular filtration rate less than 30, sinceMagnesium is eliminated by the kidneys resulting in exaggerated rise in serummagnesium.

• Patients with concomitant use of a calcium channel blocker since magnesium sulfatecould act synergistically to suppress muscular contractility.