A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)

Inclusion Criteria:

• Is at least 18 years old at the screening visit (Visit 1)

• Has a diagnosis of FECD at Visit 1

• Meets all other inclusion criteria outlined in clinical study protocol

Exclusion Criteria:

• Is a female patient of childbearing potential and any of the following is true:

1. is pregnant or lactating/breastfeeding, or

2. is not surgically sterile, not post-menopausal (no menses for the previous 12months), or not practicing an effective method of birth control as determinedby the Investigator (eg, oral contraceptives, double barrier methods, hormonalinjectable or implanted contraceptives, tubal ligation, or partner withvasectomy)

• Has a study eye with a history of cataract surgery within 90 days of Visit 1

• Meet any other exclusion criteria outlined in clinical study protocol