A Study of JNJ-90009530 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (r/r B-NHL)

Key Inclusion Criteria

• Participant must be greater than or equal to (>=) 18 years of age, at the time of signing informed consent

• All participants must have relapsed or refractory disease for each histologic subtype

• Mature aggressive large B cell NHL and Follicular Lymphoma Grade 3b: Participants must have >= 2 lines of systemic therapy or >=1 line of systemic therapy in case of participants ineligible for high-dose chemotherapy and autologous Hematopoietic stem cell transplantation (HSCT). Participants also must have had exposure to an anthracycline and an anti-CD20 targeted agent

• Follicular lymphoma Grade 1-3a and Marginal Zone Lymphoma: Participants must have >=2 prior lines of anti-neoplastic systemic therapy. Participants also must have prior exposure to an anti-CD20 monoclonal antibody

• Tumor must be cluster of differentiation (CD) 20 positive

• Measurable disease as defined by Lugano 2014 classification

• Eastern Cooperative Oncology Group (ECOG) performance status of either 0 or 1

Key Exclusion Criteria

• Diagnosis of Human herpes virus (HHV) 8-positive Diffuse large B Cell lymphoma (DLBCL)

• Prior allogeneic Hematopoietic stem cell transplantation (HSCT)

• Autologous stem cell transplant within 12 weeks of chimeric antigen receptor (CAR) T cell infusion

• Uncontrolled active infections

• History of deep vein thrombosis or pulmonary embolism within six months of infusion (except for line associated deep vein thrombosis [DVT])

• History of stroke, unstable angina, myocardial infarction, congestive heart failure ( New York Heart Association [NYHA] Class III or IV), severe cardiomyopathy or ventricular arrhythmia requiring medication or mechanical control within 6 months of screening

• History of a seizure disorder, dementia, cerebellar disease or neurodegenerative disorder

• Known history or prior diagnosis of optic neuritis or other immunologic or inflammatory disease affecting the central nervous system

• Active central nervous system (CNS) involvement by malignancy

• Current active liver or biliary disease (except for Gilbert's syndrome or asymptomatic gallstones)