Acute Effect of High Intensity Interval Exercise in Patients With Allergic Rhinitis

Last updated: March 20, 2023
Sponsor: Chulalongkorn University
Overall Status: Completed

Phase

N/A

Condition

Common Cold

Allergy (Pediatric)

Acute Rhinitis

Treatment

N/A

Clinical Study ID

NCT05779046
EX PHYSIO SPSC 5
  • Ages 18-35
  • All Genders

Study Summary

The purpose of this study was to determine the acute effect of high intensity interval exercise on respiratory function and rhinitis symptoms in allergic rhinitis patients.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Subjects had a clinical history of persistent rhinitis, and had positive skin pricktest to house dust mite (D. pteronyssinus)
  • Persistent allergic rhinitis
  • Subjects with known asthma, chronic rhinosinusitis, Lung cancer and Emphysema diseaseswere excluded.
  • BMI 18.5 - 24.9 kg/m2
  • Subjects will ask to abstain from taking antihistamine for at least 5 days,leukotriene receptor antagonist for at least 1 week, and nasal steroids for at least 2weeks prior to the start of the experiment.
  • Subjects will ask to abstain from taking any form of dietary supplement during theexperiment.
  • Subjects had no exercise training program (not exercise regularly or not exercise for 30 minutes or more at least 3 times per week during the past 6 months)

Exclusion

Exclusion Criteria:

  • Accident that are unable to continue the research, such as accidental injury orillness, etc.
  • Participants did not voluntarily participate.

Study Design

Total Participants: 12
Study Start date:
September 10, 2022
Estimated Completion Date:
December 20, 2022

Study Description

Twelve patients with allergic rhinitis aged between 19 and 31 years who had a positive skin prick test to house dust mite (D. pteronyssinus). The experiment was a crossover design in which each participant was given two types of high-intensity interval training exercise (HIT): HIT 1:1 (high intensity for 1 minute at 85-90% of maximum heart rate, then alternating with low intensity 50-55% of maximum heart rate for 1 minute) and HIT 1:2 (high intensity for 1 minute at 85-90% of maximum heart rate, then alternating with low intensity 50-55% of maximum heart rate for 2 minutes). Rhinitis symptoms, nasal blood flow, peak nasal inspiratory flow, pulmonary functions, respiratory muscle strength, and fractional exhaled nitric oxide were measured before and immediately, 15 minutes, 30 minutes, 45 minutes, and 60 minutes after exercise for each exercise program.

Connect with a study center

  • Faculty of Sports Science, Chulalongkorn University

    Pathum Wan, Bangkok 10330
    Thailand

    Site Not Available

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