COMPARISON OF DEXMEDETOMIDINE AND REMIFENTANIL FOR POSTOPERATIVE PAIN IN TRANSPHENOIDAL Pituitary SURGERY

Last updated: August 20, 2025
Sponsor: Kocaeli University
Overall Status: Completed

Phase

N/A

Condition

Chronic Pain

Post-surgical Pain

Pain

Treatment

Dexmedetomidine

Remifentanyl

Clinical Study ID

NCT05772832
KocaeliUI
  • Ages 18-65
  • All Genders

Study Summary

In patients with pituitary adenoma scheduled for endoscopic transsphenoidal pituitary surgery, it was aimed to compare the efficacy of postoperative pain relief of a selective α-2 agonist "Dexmedetomidine" and the rapid and short-acting opioid "Remifentanil" using the "Numerical Rating Scale" (NRS) administered alongside propofol in perioperative maintenance anesthesia. .

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • 18-65 years old

  • ASA-1 and ASA-2 patients

Exclusion

Exclusion Criteria:

  • Patients in need of postoperative intensive care

Study Design

Total Participants: 104
Treatment Group(s): 2
Primary Treatment: Dexmedetomidine
Phase:
Study Start date:
November 17, 2021
Estimated Completion Date:
February 22, 2023

Connect with a study center

  • University of Kocaeli

    Kocaeli, Izmit
    Turkey

    Site Not Available

  • University of Kocaeli

    Kocaeli 306970, IZMIT
    Turkey (Türkiye)

    Site Not Available

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