High- Versus Low-calcium Water for Bone Health

Inclusion Criteria:

• Body mass index ≥ 18 and < 30

• Maintenance of diet and physical activity lifestyle throughout the duration of thestudy

• Acceptance of informed consent

Exclusion Criteria:

• Consumption of water with calcium > 150 mg/L

• Pregnancy (as established by self-declaration), breastfeeding, menopause

• Inability to follow the study protocol

• Cardiac, vascular, renal, and oncological disease

• Neuropsychiatric disease, developmental disorders

• Disease or past surgery affecting the gastrointestinal tract

• Drugs that interfere with bone (e.g. corticosteroids) or with fluid balance (e.g.diuretics)