The Effect of a Lighting Intervention on Sleep in Parkinson Disease

Last updated: July 11, 2025
Sponsor: Icahn School of Medicine at Mount Sinai
Overall Status: Completed

Phase

N/A

Condition

Sleep Disorders

Insomnia

Restless Leg Syndrome

Treatment

Tailored Lighting Intervention (TLI)

Actigraph

Clinical Study ID

NCT05771558
STUDY-22-00991
  • Ages > 18
  • All Genders

Study Summary

50 participants with Parkinson's disease will be recruited to complete actigraphy studies to assess sleep disturbances. For this, participants will wear an Actigraph for seven days. Thirty of these participants with sleep disturbance will go on to receive a tailored lighting intervention (TLI) to assess the effect on sleep, fatigue, and circadian entrainment via urinary melatonin levels.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Diagnosis of Parkinson's disease and difficulties with sleep and/or cognition

Exclusion

Exclusion Criteria:

  • There are no exclusion criteria

Study Design

Total Participants: 48
Treatment Group(s): 2
Primary Treatment: Tailored Lighting Intervention (TLI)
Phase:
Study Start date:
November 14, 2022
Estimated Completion Date:
June 30, 2025

Study Description

Participants will undergo one week of baseline data collection using the actigraph and light meter and one night of an overnight urine collection. At the completion of the baseline week, the lighting intervention will be installed in the participants' home. Participants will be exposed to the lighting intervention for 2 hours each morning after awakening for 8 weeks. During the last week of the lighting, participants will be asked to wear the actigraph and light meter again for 7 days and collect one overnight urine sample. Participants will complete questionnaires before and after the intervention to further assess its effects.

Connect with a study center

  • Mount Sinai Beth Israel

    New York, New York 10003
    United States

    Site Not Available

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