Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

Last updated: February 13, 2025
Sponsor: Alumis Inc
Overall Status: Active - Not Recruiting

Phase

2

Condition

Rosacea

Skin Wounds

Warts

Treatment

ESK-001

Clinical Study ID

NCT05739435
ESK-001-007
  • Ages > 18
  • All Genders

Study Summary

This is a multi-center, open-label extension (OLE) study in patients with plaque psoriasis who have completed their participation in a previous plaque psoriasis study of ESK-001.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Must have completed a prior ESK-001 study

  • Men and Women must use highly effective methods of contraception for the entirety ofthe study

Exclusion

Exclusion Criteria:

  • Pregnancy

  • Received a prohibited concomitant medication

Study Design

Total Participants: 165
Treatment Group(s): 1
Primary Treatment: ESK-001
Phase: 2
Study Start date:
January 17, 2023
Estimated Completion Date:
December 30, 2026

Study Description

This study will consist of patients who have completed their participation in a previous plaque psoriasis study of ESK-001. Each patient will be assigned to receive ESK-001 at one of two open-label dose levels. Patients have the option to remain on study until ESK-001 is commercially available.

Connect with a study center

  • Investigator Site #2001

    Edmonton, Alberta T6G 1C3
    Canada

    Site Not Available

  • Investigator Site # 2008

    Surrey, British Columbia V3V 0C6
    Canada

    Site Not Available

  • Investigator Site #2003

    Winnipeg, Manitoba R3M 3Z4
    Canada

    Site Not Available

  • Investigator Site #1033

    Norman, Oklahoma 73071
    Canada

    Site Not Available

  • Investigator Site #2006

    London, Ontario N6H 5L5
    Canada

    Site Not Available

  • Investigator Site # 2004

    Mississauga, Ontario L4Y 4C5
    Canada

    Site Not Available

  • Investigator Site # 2007

    North Bay, Ontario PiB 3Z7
    Canada

    Site Not Available

  • Investigator Site #2005

    Oakville, Ontario L6J 7W5
    Canada

    Site Not Available

  • Investigator Site #2009

    Toronto, Ontario M3H 5Y8
    Canada

    Site Not Available

  • Investigator Site # 2002

    Waterloo, Ontario N2J 1C4
    Canada

    Site Not Available

  • Investigator Site # 2010

    Quebec, G1V 4X7
    Canada

    Site Not Available

  • Investigator Site # 1029

    Birmingham, Alabama 35205
    United States

    Site Not Available

  • Investigator Site #1001

    Phoenix, Arizona 85032
    United States

    Site Not Available

  • Investigator Site # 1023

    Rogers, Arkansas 72758
    United States

    Site Not Available

  • Investigator Site #1021

    Encinitas, California 92024
    United States

    Site Not Available

  • Investigator Site #1018

    Los Angeles, California 90045
    United States

    Site Not Available

  • Investigator Site #1007

    Santa Monica, California 90404
    United States

    Site Not Available

  • Investigator Site #1002

    Sherman Oaks, California 91403
    United States

    Site Not Available

  • Investigator site # 1030

    Fort Lauderdale, Florida 33308
    United States

    Site Not Available

  • Investigator Site #1025

    Hialeah, Florida 33012
    United States

    Site Not Available

  • Investigator site # 1028

    Miami, Florida 33175
    United States

    Site Not Available

  • Investigator Site # 1013

    Tampa, Florida 33614
    United States

    Site Not Available

  • Investigator Site #1035

    Macon, Georgia 31217
    United States

    Site Not Available

  • Investigator Site #1043

    Sandy Springs, Georgia 30328
    United States

    Site Not Available

  • Investigator Site #1005

    Rolling Meadows, Illinois 60008
    United States

    Site Not Available

  • Investigator Site # 1011

    Columbus, Indiana 47201
    United States

    Site Not Available

  • Investigator Site #1027

    South Bend, Indiana 46617
    United States

    Site Not Available

  • Investigator SIte#1036

    Overland Park, Kansas 66210
    United States

    Site Not Available

  • Investigator Site #1017

    Owensboro, Kentucky 42301
    United States

    Site Not Available

  • Investigator Site #1026

    Rockville, Maryland 20850
    United States

    Site Not Available

  • Investigator Site #1010

    Clarkston, Michigan 48346
    United States

    Site Not Available

  • Investigator Site #1031

    New Brighton, Minnesota 55112
    United States

    Site Not Available

  • Investigator Site # 1037

    Portsmouth, New Hampshire 03801
    United States

    Site Not Available

  • Investigator Site #1033

    Norman, Oklahoma 73071
    United States

    Site Not Available

  • Investigator Site #1019

    Portland, Oregon 97223
    United States

    Site Not Available

  • Investigator Site #1022

    Philadelphia, Pennsylvania 19103
    United States

    Site Not Available

  • Investigator Site # 1012

    Rapid City, South Dakota 57702
    United States

    Site Not Available

  • Investigator Site #1015

    Houston, Texas 77056
    United States

    Site Not Available

  • Investigator Site # 1006

    San Antonio, Texas 78213
    United States

    Site Not Available

  • Investigator Site # 1041

    South Jordan, Utah 84095
    United States

    Site Not Available

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