Self-Management Support for Lung Cancer Patients With Cachexia

Last updated: May 11, 2026
Sponsor: Changhua Christian Hospital
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Anorexia

Treatment

Self-management support nutrition and exercise intervention

Clinical Study ID

NCT05731076
220582
  • Ages 20-80
  • All Genders

Study Summary

The goal of this randomized clinical trial is to evaluate the efficacy of a self-management support program combining exercise and nutrition intervention for lung cancer patients with cancer cachexia anorexia syndrome.

This study is conducted in two stages. In the first stage (Pilot Phase), the researchers aim to assess the feasibility of the intervention and its potential impact on nutritional status in 20 participants. Based on these preliminary results, the intervention protocol or supervision model may be refined for the subsequent full-scale trial.

The main questions it aims to answer are:

Is the combined exercise and nutrition self-management support program feasible for lung cancer patients with cachexia?

Can this integrated intervention improve the nutritional status of these patients compared to routine care?

Participants in the intervention group will receive self-management support-based education to develop personalized exercise plans and ensure adequate protein intake. The researchers will compare this group to a control group receiving routine health education to evaluate differences in nutritional outcomes.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Diagnosed lung cancer(ICD-10 code: C33-C34)

  2. Body weight loss: body weight loss 2% before recruitment 2 months or body weightloss 5% before recruitment 6months.

  3. Physician judged may do home exercise without supervisor.

  4. Has smart phone and agree to use exercise associated application.

  5. Agree to wear Xioami smart band as long as passible.

  6. Conscious clear and communication.

  7. Eastern Cooperative Oncology Group (ECOG) 0-1.

Exclusion

Exclusion Criteria:

  1. Participants with cardiovascular disease can't exercise without supervisor.

  2. Diabetes Mellitus with blood sugar poor control.

  3. Chronic obstructive pulmonary disease with dyspnea on exertion.

  4. Platelets < 50000mm3 due to disease or treatment.

  5. Hemoglobin <10mg/dl.

  6. Recently stumble, severe pain, cognitive and behavior change.

  7. Suspect or diagnosed brain metastasis.

  8. Suspect or diagnosed bone metastasis.

  9. Receive Nasogastric tube feeding or parenteral nutrition.

  10. Physician judged can't do home exercise.

Study Design

Total Participants: 104
Treatment Group(s): 1
Primary Treatment: Self-management support nutrition and exercise intervention
Phase:
Study Start date:
January 20, 2023
Estimated Completion Date:
December 31, 2027

Connect with a study center

  • Changhua Christian Hospital

    Changhua, Changhua 51052
    Taiwan

    Site Not Available

  • Yuanlin Christian Hospital

    Changhua, Changhua 51052
    Taiwan

    Site Not Available

  • Taipei Veterans General Hospital

    Taipei, Taipei 11219
    Taiwan

    Site Not Available

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