Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds

Last updated: April 11, 2023
Sponsor: Sohag University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes And Hypertension

Treatment

N/A

Clinical Study ID

NCT05716503
Soh-Med-23-01-08
  • Ages 20-75
  • All Genders

Study Summary

The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age group 20-75 years.
  • Patients with diabetic foot wounds who are scheduled for skin grafting.

Exclusion

Exclusion Criteria:

  • Age <20 years or > 75 years.
  • An obvious septicemia.
  • Foot osteomyelitis.
  • Ulcer resulting from venous insufficiency.
  • Features of malignant ulcer.
  • Patients being treated with corticosteroids, immunosuppressive drugs.
  • Any other serious pre-existing cardiovascular, pulmonary or immunological disease.

Study Design

Total Participants: 20
Study Start date:
February 01, 2023
Estimated Completion Date:
April 30, 2024

Study Description

Negative pressure wound therapy is a new noninvasive technique for treating open wounds. It works by removing fluid from the wound bed, reducing edema, and encouraging the growth and perfusion of new granulation tissue.

Vacuum-Assisted Closure device (VAC) helps to remove fluid from open wounds through a sealed dressing and tubing which is connected to a collection container. Vacuum-assisted closure (VAC) can provide stable and persistent negative pressure, and there are several modes to choose from.

VAC has played an important role in helping to close wounds, controlling infection, promoting angiogenesis, increasing blood flow, and promoting granulation tissue growth in wounds. It is now widely applied in all kinds of acute, chronic, and special wounds with good therapeutic results. However, there is a need to pay attention to contraindications and complications of VAC when it is used, avoiding secondary damage due to improper treatment.

Connect with a study center

  • Sohag university hospital

    Sohag,
    Egypt

    Active - Recruiting

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