Retrospective Review of Esophageal Cancer at MSKCC

Phase

N/A

Condition

Digestive System Neoplasms

Esophageal Disorders

Esophageal Cancer

Treatment

Esophagectomy

Clinical Study ID

NCT05706558

16-1631

Ages > 18
All Genders

Study Summary

Residual tumor at the proximal or distal margin after esophagectomy is a known prognostic factor for poor survival outcomes in patients with esophageal cancer; however, the significance of the circumferential resection margin (CRM) remains controversial. In this study, the investigators sought to evaluate the prognostic significance of the CRM in patients with esophageal cancer undergoing resection.

Eligibility Criteria

Inclusion

Inclusion Criteria:

Histologically confirmed esophageal adenocarcinoma (EAC) or esophageal squamous cellcarcinoma (ESCC) undergoing esophagectomy
Pathologic staged T3 tumors (pT3)

Exclusion

Exclusion Criteria:

Pathologic staged T0-2 (pT0-2) or T4 tumors (pT4)
Patients with histologic types other than EAC or ESCC, dysplasia or carcinoma insitu without tumor invasion,
Patients undergoing salvage esophagectomy
Evidence of distant metastatic disease
Patients with a positive proximal or distal margin

Study Design