Cardiovascular and Cerebrovascular Control in Healthy Subjects

Last updated: March 25, 2025
Sponsor: IRCCS Policlinico S. Donato
Overall Status: Active - Recruiting

Phase

N/A

Condition

Autonomic Nervous System

Treatment

active standing

Clinical Study ID

NCT05706532
CardioSan
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability.

To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge.

The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • age >18

  • sinus rhythm

  • informed consent signed

Exclusion

Exclusion Criteria:

  • age <18

  • presence of autonomic nervous system diseases or dysfunctions

Study Design

Total Participants: 60
Treatment Group(s): 1
Primary Treatment: active standing
Phase:
Study Start date:
May 29, 2023
Estimated Completion Date:
October 31, 2027

Connect with a study center

  • IRCCS Policlinico San Donato

    San Donato Milanese, Milan 20097
    Italy

    Active - Recruiting

  • Vlasta Bari

    San Donato Milanese, Milan 20097
    Italy

    Site Not Available

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