Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis

Last updated: March 18, 2026
Sponsor: Koite Health Oy
Overall Status: Completed

Phase

N/A

Condition

Periodontitis

Treatment

Lumoral Treatment

Clinical Study ID

NCT05698823
LumoKaunas2023
  • Ages 18-85
  • All Genders

Study Summary

This study is designed to determine the efficacy of the Lumoral method in chronic periodontitis with a targeted group of stage III and IV periodontitis.

Improved supragingival plaque control can help to also sustain the subgingival plaque management in the long term.

In addition, the method might have a photobiomodulation effect on periodontal tissues.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Periodontal disease stage III-IV, according to criteria the American Academy ofPeriodontology (AAP) with at least 3 mm interdental clinical attachment level (CAL)in the site of greatest loss.

  • ≥ 18 years old

  • Presence of ≥20 teeth, including implants

  • Agreement to participate in the study and to sign a written consent form

  • Able to co-operate with the treatment protocol and avoid any other oral hygienemeasures outside of the study protocol

Exclusion

Exclusion Criteria:

  • Grade A or C periodontitis

  • Presence of any physical limitation or restriction that might restrict Lumoral use

  • Pregnancy or lactation

  • Active smoking

  • Medicated diabetes mellitus (DM)

  • Any systemic disease (e.g., wound healing dysfunctions) that could alter theprogression of periodontal disease

  • Use of antibiotics within 4 weeks week prior study

  • Periodontal treatment within 3 months prior study

  • Removable major prosthesis or major orthodontic appliance

  • A need for a hopeless teeth extraction, or open cavities in need for immediateendodontic treatment

Study Design

Total Participants: 56
Treatment Group(s): 1
Primary Treatment: Lumoral Treatment
Phase:
Study Start date:
June 06, 2023
Estimated Completion Date:
January 12, 2026

Study Description

The Lumoral Treatment is a CE-marked medical device developed to provide a potent, targeted antibacterial action on dental plaque in a home environment. The device mechanism of action is antibacterial photodynamic therapy (aPDT). The device is used by swishing a specially designed mouth rinse that strongly adheres to dental plaque. The plaque-adhered photoactive mouth rinse can be activated by a simple-to-use light applicator. Preliminary results have shown promising anti-inflammatory responses in addition to plaque reduction.

Connect with a study center

  • Hospital of Lithuanian University of Health Sciences Kaunas Clinics, Department of Dental and Oral Pathology

    Kaunas, 50161
    Lithuania

    Site Not Available

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