Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)

Inclusion Criteria:

1. Adult subjects (age ≥ 22 years) as required by local law

2. Subject has been indicated for a radical prostatectomy, radical cystectomy, ornephrectomy (partial or radical) surgical procedure

3. Subject is an acceptable candidate for a fully robotic assisted surgical procedure,a laparoscopic surgical procedure, or an open surgical procedure

4. The subject is willing to participate and consents to participate, as documented bya signed and dated informed consent form

Exclusion Criteria:

1. Subjects for which minimally invasive surgery is contraindicated as determined bythe Investigator

2. Subjects with comorbidities or medical characteristics, which would preclude thesurgical procedure in the opinion of the Investigator

3. Subjects diagnosed with a bleeding disorder and/or cannot be removed from theiranticoagulants prior to surgery based on surgeon discretion and standard-of-care

4. Non-oncology subjects with an estimated life expectancy of less than 6 months;oncology subjects considered for cystectomy with a life expectancy less than 24months; oncology subjects considered for nephrectomy with a life expectancy lessthan 60 months; oncology subjects considered for prostatectomy with less than a 10-year life expectancy.

5. Female subjects pregnant at the time of the surgical procedure.

6. Subjects who are considered to be part of a vulnerable population (e.g., prisonersor those without sufficient mental capacity)

7. Subjects who have participated in an investigational drug or device research studywithin 30 days of enrollment that would interfere with this study

8. Subjects with active infections including but not limited to pneumonia, urinarytract, cellulitis, or bacteremia