Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics

Last updated: February 28, 2025
Sponsor: M.D. Anderson Cancer Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Breast Cancer

Colorectal Cancer

Colon Cancer; Rectal Cancer

Treatment

Screening Form

Genetic Testing and Counseling

Clinical Study ID

NCT05694559
2022-0328
NCI-2023-00252
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

To identify Black individuals who are eligible for genetic testing through trusted community organizations, and to connect Black individuals and their families to genetic testing and counseling so that they can know their cancer risk and how to decrease it.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Any participant over 18 years old who self-identifies as Black or African-Americanand signs an informed consent form, also referred to as the 'Permission to Contact'form, to be part of our study.

Exclusion

Exclusion Criteria:

None

Study Design

Total Participants: 1000
Treatment Group(s): 2
Primary Treatment: Screening Form
Phase:
Study Start date:
November 23, 2022
Estimated Completion Date:
February 02, 2027

Study Description

Primary Objectives:

  • To identify 300 Black families, at least one individual per family, eligible for genetic testing using our validated simple genetic risk screening tool (GRST) 1, via collaboration with trusted community organizations. For individuals eligible for genetic testing, we will counsel them about genetic testing, including reviewing GRST results, explaining why they are eligible for genetic testing as part of standard-of-care, explaining what this entails, offering on-site or remote genetic testing, and explaining that they will be connected to a genetic counselor if they have a pathogenic mutation (PV) of a variant of unknown significance (VUS), including resources for family cascade genetic testing.

  • To provide genetic testing to 150 Black individuals and families and provide genetic counseling and risk reduction resources to individuals with a PV or VUS, including cascade genetic testing for their family members.

Connect with a study center

  • MD Anderson Cancer Center

    Houston, Texas 77030
    United States

    Active - Recruiting

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