Phase
Condition
N/ATreatment
placebo
magnesium glycinate supplement
Clinical Study ID
Ages 30-74 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Self-report of systolic blood pressure 125-159 mmHg
Measured seated systolic blood pressure 130-159 mmHg at screening visit
Body mass index less than 40 kg/m2
Total magnesium intake from supplements of no more than 100 mg/day
Willing to maintain current diet and supplement use patterns during the 12-weekintervention period
Exclusion
Exclusion Criteria:
Measured seated diastolic blood pressure 100 mmHg or greater at screening visit
Antacid or laxative use 4 times/week or more within the past 3 months
History of cardiovascular disease (myocardial infarction, stroke, revascularization [coronary artery bypass graft or percutaneous transluminal coronary angioplasty], orangina pectoris)
History of invasive cancer diagnosed within the last 5 years (non-melanoma skincancer permitted)
History of type 1 or 2 diabetes
History of renal disease
History of kidney failure
History of dialysis
History of pancreatitis
History of inflammatory bowel disease
History of hypermagnesemia
Women who are pregnant, nursing, or intend to become pregnant during the period oftreatment
Plan to relocate out of Boston area within the next year
Unwillingness and/or inability to swallow 4 pills per day
Inability to provide written informed consent
Study Design
Study Description
Connect with a study center
Brigham and Women's Hospital
Boston, Massachusetts 02215
United StatesSite Not Available
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