Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal Cords

Last updated: May 5, 2023
Sponsor: Eye & ENT Hospital of Fudan University
Overall Status: Active - Recruiting

Phase

1/2

Condition

N/A

Treatment

Curcumin

Mitomycin-C

Clinical Study ID

NCT05688488
2022011-1
  • Ages 18-75
  • All Genders

Study Summary

To provide a novel therapy idea and method to solve the clinical problem of postoperative adhesion of bilateral vocal cords, patients enrolled in this study will be applied with curcumin on both wound sites of bilateral vocal cords after the surgery on the bilateral vocal cord endoscopically.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Patients with bilateral vocal cord diseases who are going to undergo resection ofbilateral vocal cord lesions endoscopically.
  2. Patients with bilateral vocal cord adhesion who are going to undergo incision ofbilateral vocal cord adhesion endoscopically.

Exclusion

Exclusion Criteria:

  1. Patients with other laryngeal diseases.
  2. Patients with cardiac and pulmonary insufficiency.
  3. Patients unable to cooperate with the follow-up on time after surgery.
  4. Patients who refuse to sign the informed consent after notification.
  5. Patients who have a severe allergic disease or allergic history to a variety of drugs.
  6. Other circumstances that are not appropriate to be included in the clinical trial.

Study Design

Total Participants: 100
Treatment Group(s): 2
Primary Treatment: Curcumin
Phase: 1/2
Study Start date:
May 05, 2023
Estimated Completion Date:
December 31, 2026

Connect with a study center

  • Eye & ENT Hospital of Fudan University

    Shanghai, Shanghai 200031
    China

    Active - Recruiting

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