Phase
Condition
Weight Loss
Obesity
Diabetes And Hypertension
Treatment
6-months of medically assisted glycemic improvement
Bariatric surgery
Clinical Study ID
Ages 18-60 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Study 1:
Age: 18-60 years
BMI: 18.5 - 39, minimum weight = 50kg
Chronic hyperglycemia: HbA1c of ≥ 70 mmol/mol with a duration of ≥ 2 months prior toenrollment
Physical activity: Less than 3 x 60 min of structured physical activity per week
Study 2 & 3:
Age: 25-60 years
BMI: ≥ 35
Physical activity: Less than 3 x 60 min of structured physical activity per week
Healthy Control Participants:
Age: 18-60 years
BMI: 18.5 - 30, minimum weight = 50kg
Physical activity: Less than 3 x 60 min of structured physical activity per week
Exclusion
Exclusion Criteria:
Study 1, 2, 3 and healthy controls:
Diabetic neuropathy with expected motor deficits
Uncontrolled cardiovascular or pulmonary disease, peripheral vascular disease,osteoarthropathy of the lower extremity, or any neurological og rheumatologicaldisease which may affect muscle function, as well as any other disease that mayeffect ones ability to perform physical activity.
Any Magnetic Resonance contraindications
Any condition that by the principal investigator is expected to affect theparticipants ability to execute the study elements
Specifically for healthy control participants:
- The presence of diabetes or pre-diabetes (HbA1c ≥42 mmol/mol)
Study Design
Connect with a study center
Aarhus University Hospital, Denmark
Aarhus, 8000
DenmarkSite Not Available
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