US and MRI of the Forefoot: Intermetatarsal Bursitis or Morton's Neuroma

Last updated: November 13, 2024
Sponsor: Rigshospitalet, Denmark
Overall Status: Active - Enrolling

Phase

N/A

Condition

Bursitis

Treatment

Ultrasound

MRI with contrast

Clinical Study ID

NCT05685160
H-20067346
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The aim of this study is to investigate the incidence of intermetatarsal bursitis and Morton's neuroma in patients with metatarsalgia (i.e. pain in the forefoot) and control subjects by diagnostic imaging with ultrasound and MRI.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age > 18 years

  • Pain in an intermetatarsal space (patient group)

Exclusion

Exclusion Criteria:

  • Age <18 years

  • Open wounds or ongoing infection in the forefoot at the time of examination

  • Persons with contraindications to participate in MRI scan

  • Persons with a history of significant trauma in the forefoot, e.g. any fracture orprevious surgeries in the forefoot

  • Persons who have previously received treatment for Morton's neuroma in the samefoot, e.g. injection (within 6 months) or operation (anytime)

  • Persons with severely impaired renal function (GFR <30 ml/min)

  • Persons with a systemic inflammatory condition like rheumatoid arthritis, due toclinically silent intermetatarsal bursitis in this group (control group)

Study Design

Total Participants: 75
Treatment Group(s): 2
Primary Treatment: Ultrasound
Phase:
Study Start date:
June 14, 2021
Estimated Completion Date:
March 31, 2027

Study Description

In a group of patients with intermetatarsal pain found by an orthopedic surgeon, the investigators want to assess the incidences of intermetatarsal bursitis and Morton's neuroma, using diagnostic imaging; ultrasound and MRI.

The hypothesis is, that intermetatarsal bursitis is an overlooked diagnosis in patients with metatarsalgia. As a result of sparse literature and lack of knowledge about this condition with symptoms mimicking Morton's neuroma, a part of patients diagnosed with Morton's neuroma, suffers from intermetatarsal bursitis instead.

Additionally, the investigators want to evaluate the clinical sign opening toes.

Based on clinical photos of the feet, the investigators want to document the presence of opening toes and investigate if there is a correlation with either intermetatarsal bursitis and/or Morton's neuroma.

Connect with a study center

  • Department of Radiology

    Copenhagen, 2100
    Denmark

    Site Not Available

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