Balance Tele-Rehab in Parkinson's Disease Parkinson's Disease

Last updated: November 3, 2023
Sponsor: Oregon Health and Science University
Overall Status: Active - Recruiting

Phase

N/A

Condition

N/A

Treatment

Balance Tele-Rehabilitation Agility Boot Camp (ABC)

Clinical Study ID

NCT05680597
1R01HD107074-01
1R01HD107074-01A1
  • Ages 55-85
  • All Genders

Study Summary

This project will determine the feasibility and efficacy of remote assessment and treatment of balance disorders in people with Parkinson's disease.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Diagnosis of idiopathic PD from movement disorders neurologist with the United KingdomBrain Bank criteria of bradykinesia and one or more of the following - rest tremor,rigidity, and balance problems not from visual, vestibular, cerebellar orproprioceptive conditions
  2. responsive to levodopa (self-reported)
  3. Hoehn & Yahr stages I-III;
  4. ages 55-85 years old
  5. ability to follow directions in order to participate in testing procedures andexercise classes
  6. free of any medical conditions or medication that contraindicates participation in anexercise program
  7. willing and able to participate in rehabilitation intervention approximately 3x/weekfor 4 weeks while also refraining from making changes to medications (as reasonable)or to other exercise programs during the study period.

Exclusion

Exclusion Criteria:

  1. Major musculoskeletal or neurological disorders, structural brain disease, epilepsy,acute illness or health history, other than PD, significantly affecting gait andbalance (i.e., musculoskeletal disorder, vestibular problem, head injury, stroke,cardiac disease, etc.)
  2. no medical condition that precludes exercise
  3. cognitive inability to participate in an exercise program, such as MoCA score lessthan or equal to 19, prior diagnosis of dementia or inability to follow directions
  4. recurrent fallers, defined as those who fall more than 3 times a week (from patientand caregiver recollection)
  5. excessive use of alcohol or recreational drugs
  6. recent change in medication
  7. inability to stand and walk for ISAW without an assistive device.

Study Design

Total Participants: 80
Treatment Group(s): 1
Primary Treatment: Balance Tele-Rehabilitation Agility Boot Camp (ABC)
Phase:
Study Start date:
September 19, 2022
Estimated Completion Date:
June 30, 2027

Study Description

This project consists of a virtual balance assessment which will use objective measures of balance and gait obtained with wearable sensors on the feet and waist. During a virtual assessment, the Modified Instrumented Stand and Walk Test (ISAW) will be conducted in 80 people with Parkinson's disease (PD) to predict a gold-standard, clinical in-person assessment of balance, the Mini-Balance Evaluation System Test (Mini-BESTest). For the balance rehabilitation there will be 80 participants randomized into two groups: 1) unsupervised home Agility Boot Camp (ABC) exercises (standard of care), 2) telerehabilitation with therapist conducting the ABC exercise program. Mobility during daily life will be measured using wearable sensors to explore if improvements after rehabilitation transfer to daily life mobility. The long-term goal of this project is to develop a more effective, home-based balance assessment and treatment that can be used in older adults with balance impairments to improve safe mobility during daily life.

Connect with a study center

  • Oregon Health Science University

    Portland, Oregon 97239
    United States

    Active - Recruiting

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