Phase
Condition
Dementia
Memory Loss
Mild Cognitive Impairment
Treatment
Additional neuropsychological tests
Electroencephalogram (EEG) system
Standard Neuropsychological Testing
Clinical Study ID
Ages 20-90 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
For Mild Alzheimer Disease (AD) dementia
Meets probable AD dementia National Institute on Aging and Alzheimer's Association (NIA-AA) criteria
50-90 years old
Mini-Mental State Examination (MMSE) 20-27
Performance on delayed recall and recognition memory worse than 1.5 standarddeviation (SD) for age and education
Performance on delayed recall and recognition memory worse than 1.5 SD for age &education in at least one other cognitive domain (e.g., language, executivefunctioning) based on other tests in our neuropsychological test battery.
Dr. Turk and Dr. Budson will confirm all mild AD dementia diagnoses
For Mild cognitive impairment (MCI)
MCI due to any etiology 50-90 years old
MMSE > 23
Performance on delayed recall and recognition memory worse than 1.0 SD for age &education adjusted norms
Dr. Turk and Dr. Budson will confirm all MCI diagnoses
For Healthy older adults
50-90 years old
Functioning normally in occupation determined by self-report
For Healthy younger adults
20-50 years old
Functioning normally in occupation determined by self-report
Exclusion
Exclusion Criteria:
A clinically significant problem of any of the following conditions:
depression
heavy alcohol or drug use
cerebrovascular disease
a different degenerative disease (e.g., fronto-temporal dementia, Parkinson'sdisease)
any medical condition whose severity could significantly impair cognition (e.g.,organ failure)
on any antipsychotic or epilepsy medication
Unable to understand the consent form
Study Design
Study Description
Connect with a study center
BU Alzheimer Disease Center
Boston, Massachusetts 02118
United StatesSite Not Available
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