Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy

Last updated: April 5, 2024
Sponsor: Gangnam Severance Hospital
Overall Status: Active - Recruiting

Phase

N/A

Condition

Urologic Cancer

Prostate Cancer

Prostate Cancer, Early, Recurrent

Treatment

conventional PEEP

optimized PEEP

Clinical Study ID

NCT05669443
3-2022-0361
  • Ages 20-70
  • Male

Study Summary

Steep trendelenburg posture or pneumoperitoneum for surgery causes ventilation problems during surgery, so finding a way to overcome is a challenging task for anesthesiologists. In this study, for patients undergoing robot assisted laparoscopic prostatectomy under general anesthesia, anesthesia is going to perform by applying conventional positive end-expiratory pressure (PEEP 5cmH2O) or individually determined positive end-expiratory pressure values for each patient using electrical impedance tomography. We plan to compare intraoperative ventilation through arterial blood gas analysis to find out the way to improve intraoperative ventilation.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. 20 - 70 years of age who are scheduled for robotic assisted laparoscopic prostatectomyat the Department of Urology, Gangnam Severance Hospital,
  2. ASA-PS (American Society of Anesthesiology Body Rating) I-IlI,
  3. Patients with a BMI of 35 kg/m2 or less

Exclusion

Exclusion Criteria:

  1. Patients with lung disease
  2. BMI >35kg/m2
  3. Patients for whom positive end-tidal pressure cannot be applied (large bullae, severecardiac disease)
  4. patient refusal

Study Design

Total Participants: 42
Treatment Group(s): 2
Primary Treatment: conventional PEEP
Phase:
Study Start date:
April 03, 2023
Estimated Completion Date:
November 10, 2024

Connect with a study center

  • Gangnam Severacne Hospital Yonsei University College of Medicine

    Seoul,
    Korea, Republic of

    Active - Recruiting

Not the study for you?

Let us help you find the best match. Sign up as a volunteer and receive email notifications when clinical trials are posted in the medical category of interest to you.