A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain

Last updated: March 9, 2025
Sponsor: Jocelyn Fitzgerald
Overall Status: Active - Not Recruiting

Phase

3

Condition

Urinary Tract Infections

Urinary Incontinence

Dysmenorrhea (Painful Periods)

Treatment

Pelvic floor physical therapy

Behavioral health consultation/therapy

Usual Urogynecologic care

Clinical Study ID

NCT05658874
STUDY21060060
  • Ages 18-99
  • Female

Study Summary

The goal of this clinical trial is to compare two different treatment patterns in patients with chronic bladder pain. The main questions the investigators are seeking to answer is if bladder pain improves before and after treatment using a painful bladder scale. The participant will have 5 visits to evaluate your symptoms with questionnaires, at least one procedural visit, and must participate in physical therapy and some kind of behavioral health therapy. This study will assess participant response to a bundled-care approach to chronic bladder pain both pre-and post intervention as well as compared to a group of participants receiving typical care.

Eligibility Criteria

Inclusion

  • Inclusion Criteria:

  • Female patient 18 years of age or older

  • diagnosis of Interstitial Cystitis/Painful Bladder Syndrome, scoring 6 points orhigher on O'Leary Sant Questionnaire

Exclusion

  • Exclusion Criteria:

Active pelvic or bladder infection within past 2 weeks

  • contraindications to medications or intervention therapeutics

  • inability to speak or read English

  • pelvic floor interventional procedure including bladder instillations 4 weeks priorto study recruitment

  • meets criteria for diagnostic laparoscopy

  • internal referral (to reduce severity bias)

Note: patients are not excluded for currently taking any medication on the treatment list.

Patients can be treated for UTI during the study period.

Study Design

Total Participants: 26
Treatment Group(s): 9
Primary Treatment: Pelvic floor physical therapy
Phase: 3
Study Start date:
December 01, 2022
Estimated Completion Date:
October 31, 2025

Study Description

Objectives:

The goals of this research program are to evaluate the patient-reported outcomes of a multimodal care bundle for patients presenting to a multidisciplinary chronic pelvic pain clinic compared to "usual care" in an Urogynecology clinic.

Primary Aim:

To compare pre and post intervention self-evaluation of pain and function scores in women with chronic pain syndromes with a primary finding of urinary/bladder pain symptoms with or without levator spasm who undergo multi-disciplinary, bundled care compared with usual care in a Urogynecology clinic setting.

Secondary Aims:

a) To identify and phenotype "non-responders" to a bundled approach to Interstitial Cystitis/Painful Bladder Syndrome/Chronic Pelvic Pain (IC/PBS/CPP).

Hypothesis: We hypothesize that a bundled, multidisciplinary care approach will significantly improve patient scores on validated outcomes questionnaires compared to usual care.

Methods:

All treatment plans, medications, and procedures recommended for patients involved in this study are within the current standards of care for IC/PBS/CPP, regardless of treatment arm and are known to be safe interventions.

Study Design: Single center, randomized pre-post intervention/prospective cohort study32 of usual FPMRS care vs. multimodal, multidisciplinary care bundle (MMCB).

Setting: Patients will be recruited from an outpatient Urogynecology clinic. They will subsequently be randomized to a Multidisciplinary chronic pelvic pain clinic at an alternate site vs. continuing usual outpatient care in Urogynecology as above.

Connect with a study center

  • Magee Womens Hospital

    Pittsburgh, Pennsylvania 15213
    United States

    Site Not Available

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