Phase
Condition
Pain (Pediatric)
Oral Facial Pain
Headaches
Treatment
Pressure pain thresholds (PPT)
Pain ratings
Thermal Stimuli
Clinical Study ID
Ages 10-13 All Genders Accepts Healthy Volunteers
Study Summary
Eligibility Criteria
Inclusion
Inclusion criteria for healthy participants:
Age 10-13
Males or females (biological sex)
Not diagnosed with migraine or having migraine symptoms
With a first degree relative diagnosed with migraine (for the Fam-His group) or without a first or a second degree relative diagnosed with migraine (for the No-Fam-His group)
Inclusion criteria for participants with migraine:
Age 10-13
Males or females (biological sex)
Diagnosed with migraine or having migraine symptoms
Migraine duration > 6 months
Without preventative treatment or with stable preventative treatment for migraine (no change in intervention in the last 6 months)
Exclusion Criteria for the healthy group:
- Participants will not be enrolled if any of the following criteria exist and based on the investigator discretion:
Diagnosis of any chronic pain syndrome
Diagnosis of a neurological, developmental, pubertal, or psychiatric disorder
Taking pain or psychiatric medications regularly
Having an MRI contraindication such as metal in the body or claustrophobia
Not able to understand and communicate in English
Exclusion Criteria for the migraine group
- Participants will not be enrolled if any of the following criteria exist and based on the investigator discretion:
Diagnosis of any chronic pain syndrome other than migraine
Diagnosis of a neurological, developmental, pubertal, or psychiatric disorder
Having an MRI contraindication such as metal in the body or claustrophobia
Not able to understand and communicate in English
Study Design
Study Description
Connect with a study center
Washington University School of Medicine
Saint Louis, Missouri 63110
United StatesActive - Recruiting
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