Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome

Last updated: March 28, 2025
Sponsor: Boston Children's Hospital
Overall Status: Active - Not Recruiting

Phase

N/A

Condition

Down's Syndrome

Treatment

Psychoeducational Curriculum

JASPER

Clinical Study ID

NCT05638412
P00043317
  • Ages 36-90
  • All Genders

Study Summary

In this study, investigators will study the impact of a 1:1 caregiver coaching intervention using the JASPER (Joint Attention, Symbolic Play, Engagement, Regulation) behavioral therapy curriculum compared to a psychoeducational curriculum that will be provided to caregivers for self-directed learning. Investigators want to determine the impact of both interventions on the child's development and behavior, and caregiver implementation of strategies.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Confirmed diagnosis of Trisomy 21

  • Age 3-7 years

  • Able to walk independently

  • English speaking

  • Caregiver able to complete either 1:1 virtual coaching sessions or psychoeducationalbehavioral curriculum

Exclusion

Exclusion Criteria:

  • Mosaic Down syndrome

  • Significant and uncorrected hearing and/or vision problems

Study Design

Total Participants: 57
Treatment Group(s): 2
Primary Treatment: Psychoeducational Curriculum
Phase:
Study Start date:
January 23, 2023
Estimated Completion Date:
August 31, 2025

Study Description

Down syndrome (DS), the most common genetic cause of intellectual disability, can be associated with a wide range of developmental needs. Behavioral challenges are common, and can impact learning, overall achievement, relationships, inclusion in schools, and community integration.

The goal of this study is to determine whether JASPER (Joint Attention Symbolic Play Engagement and Regulation) can improve caregiver implementation of behavioral strategies, caregiver self-efficacy and confidence, and child development.

Participants will be randomized to receive either the JASPER intervention or a caregiver psychoeducational group. Participants in the JASPER intervention will receive 10 weekly virtual educational sessions utilizing JASPER therapy modules through 1:1 parent-child coaching sessions. Caregivers in the comparison group will receive 10 weekly modules containing a psychoeducational curriculum. The outcome measures will assess caregiver responsiveness, child joint engagement with caregiver, caregiver self-efficacy, and child behavior, language, and adaptive skills.

Connect with a study center

  • Boston Children's Hospital

    Boston, Massachusetts 02445
    United States

    Site Not Available

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