Development and Validation of a Deep Learning System for Nasopharyngeal Carcinoma Using Endoscopic Images

Last updated: November 23, 2022
Sponsor: Eye & ENT Hospital of Fudan University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Nasopharyngeal Cancer

Carcinoma

Treatment

N/A

Clinical Study ID

NCT05627310
AIAD202204
  • All Genders

Study Summary

Develop a deep learning algorithm via nasal endoscopic images from eight NPC treatment centerto detect and screen nasopharyngeal carcinoma(NPC).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • The quality of endoscopic images should clinical acceptable.
  • Patients were diagnosed with biopsy(NPC, benign hyperplasia). Control corhort(normalnasopharynx) don't require bispsy result.

Exclusion

Exclusion Criteria:

  • images with spots from lens flares or stains, and overexposure were excluded fromfurther analysis.
  • image can not expose most part of lesion clearly.

Study Design

Total Participants: 50000
Study Start date:
November 01, 2022
Estimated Completion Date:
March 31, 2024

Study Description

Nasopharyngeal carcinoma (NPC) is an epithelial cancer derived from nasopharyngeal mucosa. Nasal endoscopy is the conventional examination for NPC screening. It is a major challenge for inexperienced endoscopists to accurately distinguish NPC and other benign dieseases. In this study, we collcet multi-center endoscopic images and train a deep learning model to detect NPC and indicate tumor location. Then, the model perfomance will be compared with endoscopists and be tested prospectively with external dataset.

Connect with a study center

  • Fujian Medical University Union Hospital

    Fuzhou, Fujian
    China

    Active - Recruiting

  • Quan Zhou First Affiliated Hospital of Fujian Medical University

    Quanzhou, Fujian
    China

    Active - Recruiting

  • The People' s Hospital of Jiangmen

    Jiangmen, Guangdong
    China

    Active - Recruiting

  • First Affiliated Hospital of Guangxi Medical University

    Nanning, Guangxi
    China

    Active - Recruiting

  • The People' s Hospital of Guangxi Zhuang Autonomous Region

    Nanning, Guangxi
    China

    Active - Recruiting

  • Xiangya Hospital of Central South University

    Changsha, Hunan
    China

    Active - Recruiting

  • The First Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi
    China

    Active - Recruiting

  • Eye&ENT Hospital of Fudan University

    Shanghai, Shanghai
    China

    Active - Recruiting

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