Phase
Condition
Chest Pain
Hyponatremia
Congestive Heart Failure
Treatment
COMBO
PRIME
Clinical Study ID
Ages > 65 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
Subjects must be able to communicate meaningfully with the investigator and must belegally competent to provide written informed consent.
Subjects may be of either sex with age > 65 years.
Subjects must be diagnosed with HFrEF as per established echocardiographic criteria (New York Heart Association Class II-III) with an ejection fraction <45%.
Cardiologist approve after thorough chart review and physical examination
Hemoglobin of at least 10.0 g/dL
Exclusion
Exclusion Criteria:
Progressive worsening of exercise tolerance or dyspnea at rest or on exertion overprevious 3-5 days
Significant ischemia at low exercise intensities (<2 METS or ~50 W)
Uncontrolled diabetes (HbA1c >10%)
Acute systemic illness of fever
Recent embolism (in the 6 weeks)
Deep Vein Thrombophlebitis
Active pericarditis or myocarditis
Severe aortic stenosis (aortic valve area <1.0 cm2)
Regurgitant valvular heart disease requiring surgery
Myocardial infarction within previous 3 weeks
New onset atrial fibrillation (in the last 4 weeks)
Resting Heart Rate >120bpm
Study Design
Study Description
Connect with a study center
University of Virginia, Department of Kinesiology
Charlottesville, Virginia 22908
United StatesActive - Recruiting
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