The Effects and Mechanisms of Mindfulness Intervention for Emotional Distress

Last updated: November 7, 2022
Sponsor: Peking University
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mood Disorders

Kleptomania

Treatment

N/A

Clinical Study ID

NCT05606224
NCRC2021M01
  • Ages 18-65
  • All Genders

Study Summary

Traditional offline interventions such as MBCT and MBSR have been implemented in treating patients with emotional disorders and obtained significantly improved clinical outcome. However, these offline interventions require the involvement of a therapist expertized in mindfulness and usually charge a high fee, which may not be accessible and cost-effective for lots of patients with psychological disorders. Fortunately, online self-help interventions can compensate for these disadvantages. Our research team has developed a self-help online mindfulness program targeting emotional distress (i.e., MIED), which has been demonstrated to be effective for individuals with emotional distress in a preliminary study. Since patients with emotional disorders usually suffered from emotional distress, the current study will apply this program to these patients, and investigate its auxiliary effects on patients' psychological and physical health.

The primary aim of the current study is to evaluate the effectiveness of MIED for patients with emotional disorders. To do so, we will use a design in which patients who receive online mindfulness training (MIED) except for treatment as usual (TAU) will be compared with patients who receive TAU alone. We expect the intervention to improve patients' psychopathological symptoms reported by the patients and the clinicians or the research team and increase their overall functioning, positive mental health, and physical health compared to TAU. In addition, previous studies have shown that mindfulness interventions improve psychological symptoms through improving cognitive flexibility, distress tolerance, intolerance of uncertainty, and experiential avoidance. Therefore, the secondary aim of the study is to examine the mediating effect of these factors on the relationships between mindfulness practice and improvements in outcome variables.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Age 18-65;
  • Diagnosis of emotional disorders, including anxiety disorders (e.g., panic disorder,social anxiety disorder, generalized anxiety disorder), and unipolar depressiondisorders;
  • If taking medication, haven't changed for at least 4 weeks before intervention onset,and no change in medicine is expected;
  • Voluntary participation in this study and sign an informed consent form.

Exclusion

Exclusion Criteria:

  • No access to the internet;
  • Inadequate proficiency in Chinese;
  • Previous participation in mindfulness-based programs longer than 6 weeks, and/orcurrent practice of meditation more than once per week;
  • A history of schizophrenia or schizoaffective disorder, current organic mentaldisorders, substance abuse disorder, and pervasive developmental disorders;
  • Manifesting with any self-injury or suicidal risks.

Study Design

Total Participants: 200
Study Start date:
February 20, 2022
Estimated Completion Date:
August 30, 2023

Connect with a study center

  • Beijing Anding Hospital

    Beijing, Beijing
    China

    Active - Recruiting

  • Beijing Tiantan Hospital

    Beijing, Beijing
    China

    Active - Recruiting

  • Fosha Mental Health Center

    Foshan, Guangdong
    China

    Active - Recruiting

  • Nanjing Brain Hospital

    Nanjing, Jiangsu
    China

    Active - Recruiting

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