Brain Enhancement Training Towards Elders Resilience to Aging, Phase IIB

Inclusion Criteria:

• Participant must be 70 years of age or older

• Participant must be a fluent English speaker

• Participant must have adequate sensorimotor capacity to perform the program,including visual capacity adequate to read from a computer screen at a normalviewing distance, auditory capacity adequate to understand normal speech, and motorcapacity adequate to control a computer mouse

• Participant must not have evidence of dementia as indicated by the MontrealCognitive Assessment (MoCA)

Exclusion Criteria:

• Participant with any medical illnesses, injuries or conditions predisposing toimminent functional and/or cognitive decline

• Participant requiring caregiver assistance in dressing/personal hygiene

• Participant with severe visual deficits (including visual neglect, partial fieldcuts, anopias) and/or severe hearing deficit that would prevent use of thecomputerized treatment program

• Participant with recent participation of computer-delivered cognitive trainingwithin 2 years of consent

• Participant with claustrophobia or any other contraindication to MRI scanning

• Participant with inability to complete a 1-hour MRI

• Pregnant women

• Participant with any implanted devices above the waist (e.g., cardiac pacemaker orauto-defibrillators, neural pacemaker, aneurysm clips, cochlear implant, metallicbodies in the eye or central nervous system, any form of wires or metal devices thatmay concentrate radio frequency fields)

• Participants with active suicidal ideation with specific plan and intent orsuicide-related behaviors within 2 months of consent as measured by theColumbia-Suicide Severity Rating Scale (C-SSRS)