Experience With Topical Acne Treatment

Last updated: May 27, 2025
Sponsor: Wake Forest University Health Sciences
Overall Status: Active - Recruiting

Phase

1

Condition

Rash

Acne

Scalp Disorders

Treatment

Adapalene Gel

adapalene, benzoyl peroxide gel, and clindamycin phosphate gel every day.

Adapalene Gel and the clindamycin phosphate/benzoyl peroxide gel

Clinical Study ID

NCT05582434
IRB00089304
  • Ages 18-85
  • All Genders

Study Summary

Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Adult patients ≥18 years of age

  2. Patients with a current diagnosis of acne

  3. Patients who live in the US,

  4. Patients have sufficient command of the English language

Exclusion

Exclusion Criteria:

  1. Patients less than the age of 18

  2. Patients without a current diagnosis of acne

  3. Patients who do not live in the US

  4. Patients without a sufficient command of the English language

Study Design

Total Participants: 72
Treatment Group(s): 3
Primary Treatment: Adapalene Gel
Phase: 1
Study Start date:
February 15, 2024
Estimated Completion Date:
November 30, 2026

Connect with a study center

  • Wake Forest University Health Sciences

    Winston-Salem, North Carolina 27157
    United States

    Active - Recruiting

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