Real-time Deflectable Guidewire in Neuro-interventions Study

Inclusion Criteria:

• >18 years of age
• Informed consent signed by patient
• Confirmed cerebral unruptured aneurysm treatable via transcatheter approach

Exclusion Criteria:

• Pregnancy or lactation
• Known disorder of vascular fragility with propensity to vascular injury (e.g.,Ehlers-Danlos syndrome)
• Known prior vascular stenosis or dissection or injury to vessels intended to becatheterized during study procedures
• Acute phase myocardial infarction or uncontrolled cardiac arrhythmia
• Uncontrolled serum electrolyte imbalance
• Bleeding disorder which limits the use of antiplatelet and/or anticoagulant therapy
• Known contraindication to intravascular contrast material that cannot be adequatelycontrolled with pre-medication
• Known hypersensitivity to Nickel
• Subjects currently enrolled in another investigational device or drug study thatclinically interferes with the current study endpoints