Real-time Deflectable Guidewire in Neuro-interventions Study

Inclusion Criteria:

• >18 years of age

• Informed consent signed by patient

• Confirmed cerebral unruptured aneurysm treatable via transcatheter approach

Exclusion Criteria:

• Pregnancy or lactation

• Known disorder of vascular fragility with propensity to vascular injury (e.g.,Ehlers-Danlos syndrome)

• Known prior vascular stenosis or dissection or injury to vessels intended to becatheterized during study procedures

• Acute phase myocardial infarction or uncontrolled cardiac arrhythmia

• Uncontrolled serum electrolyte imbalance

• Bleeding disorder which limits the use of antiplatelet and/or anticoagulant therapy

• Known contraindication to intravascular contrast material that cannot be adequatelycontrolled with pre-medication

• Known hypersensitivity to Nickel

• Subjects currently enrolled in another investigational device or drug study thatclinically interferes with the current study endpoints