Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma

Inclusion Criteria:

• Mild to moderate, primary open angle glaucoma
• Characteristics consistent with mild to moderate glaucoma
• Use of 1 - 4 ocular hypotensive medications at the Screening exam and meets the IOP (intraocular pressure) criteria
• Visually significant cataract

Exclusion Criteria: Any of the following prior treatments for glaucoma (study eye):

• Laser Trabeculoplasty
• Endocyclophotocoagulation (ECP) or Micropulse laser
• iStent or iStent Inject
• Hydrus Microstent
• Trabeculectomy or other bleb forming procedure including Xen, Express, and glaucomadrainage device/valve.
• Prior canaloplasty (ab-interno and ab-externo)
• Suprachoroidal stent (e.g., Cypass, iStent Supra, XEN)
• Concurrent IOP-lowering procedure other than use of the iTrackTM Advance canaloplastydevice at the time of surgery (e.g., ECP, CPC, etc.)
• Previous treatment with iTrack (Note: permitted if fellow eye only was treated)
• Acute angle closure, traumatic, congenital, malignant, uveitic or neovascularglaucoma, pigmentary glaucoma or pseudo exfoliative glaucoma.