Cataract Surgery in Conjunction With Ab-interno Canaloplasty Compared to Cataract Surgery Only in Patients With Mild to Moderate Primary Open-Angle Glaucoma

Inclusion Criteria:

• Mild to moderate, primary open angle glaucoma

• Characteristics consistent with mild to moderate glaucoma

• Use of 1 - 4 ocular hypotensive medications at the Screening exam and meets the IOP (intraocular pressure) criteria

• Visually significant cataract

Exclusion Criteria:

Any of the following prior treatments for glaucoma (study eye):

• Laser Trabeculoplasty

• Endocyclophotocoagulation (ECP) or Micropulse laser

• iStent or iStent Inject

• Hydrus Microstent

• Trabeculectomy or other bleb forming procedure including Xen, Express, and glaucomadrainage device/valve.

• Prior canaloplasty (ab-interno and ab-externo)

• Prior goniotomy, or trabeculotomy (ab-interno or ab-externo)

• Suprachoroidal stent (e.g., Cypass, iStent Supra, XEN, MINIject)

• Concurrent IOP-lowering procedure other than use of the iTrackTM Advancecanaloplasty device at the time of surgery (e.g., ECP, CPC, etc.)

• Previous treatment with iTrack (Note: permitted if fellow eye only was treated)

• Acute angle closure, traumatic, congenital, malignant, uveitic or neovascularglaucoma