Effects of Peppermint Oil in Mild-moderate Hypertension.

Last updated: August 9, 2024
Sponsor: University of Central Lancashire
Overall Status: Active - Recruiting

Phase

N/A

Condition

Diabetes Prevention

Stress

Circulation Disorders

Treatment

Peppermint oil

Placebo

Clinical Study ID

NCT05561543
Peppermint oil hypertension
  • Ages 18-65
  • All Genders

Study Summary

Cardiovascular and associated hypertensive diseases are the leading health burden and cause of mortality worldwide; therefore, the necessity for effective interventions is paramount. Dietary interventions to improve cardiovascular health are highly sought after as they possess less risk and financial burden than pharmacological drugs. Our previous randomized trial has shown that oral peppermint can improving systolic blood pressure and other cardiovascular/ blood lipids in healthy individuals. However, to date, no research has explored this using a placebo randomized intervention in patients with hypertension.

Therefore, the primary purpose of the proposed investigation is to test the ability of oral peppermint oil supplementation to improve cardiometabolic parameters in participants with mild-moderate hypertension.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. Aged from 18-65 years

  2. Systolic blood pressure 120 to 139 mmHg

  3. Not taking prescribed medicine for blood pressure management

  4. have the ability to complete written questionnaires independently

  5. Able to provide informed consent

Exclusion

Exclusion Criteria:

  1. Diagnosed with diabetes mellitus and/ or coronary heart disease

  2. Pregnant and lactating women

  3. Allergy to peppermint

  4. Habitual consumption of peppermint products

  5. Regular consumption of antioxidant supplements

(5) Body mass index larger than 40.0 kg/m2 (6) Current enrolment in other clinical trials of other external therapies

Study Design

Total Participants: 40
Treatment Group(s): 2
Primary Treatment: Peppermint oil
Phase:
Study Start date:
January 01, 2024
Estimated Completion Date:
September 01, 2025

Connect with a study center

  • University of Central Lancashire

    Preston, Lancashire PR4 0PE
    United Kingdom

    Active - Recruiting

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