Last updated: April 23, 2024
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Overall Status: Active - Recruiting
Phase
N/A
Condition
Coronary Artery Disease
Vascular Diseases
Atherosclerosis
Treatment
N/AClinical Study ID
NCT05559918
AUMC25485
Ages > 18 All Genders
Study Summary
Eligibility Criteria
Inclusion
Inclusion Criteria:
- Adult men and women aged at least 18 years
- Scheduled for diagnostic CAG due to suspected obstructive coronary artery disease
Exclusion
Exclusion Criteria:
- Presence of contra-indications for the use of clopidogrel (hypersensitivity or knownallergy to clopidogrel, severe liver insufficiency, resent or active pathologicalbleeding, patients known to be poor CYP2C19 metabolizers, patients usingpharmacological CYP2C19 inhibitors and inducers)
- Patients using clopidogrel for other reasons than the scheduled diagnostic CAG (e.g.due to previous stroke)
- Patients using P2Y12 inhibitors other than clopidogrel (e.g. prasugrel, ticagrelor,cangrelor)
- Patients using VKA (e.g. acenocoumarol, fenprocoumon)
- Patients using DOAC/NOAC (e.g. apixaban, dabigatran, edoxaban, rivaroxaban)
- Inability to give informed consent (e.g., language barrier)
- Patients who have a documented mentioning of previous denial to any trialparticipation in the electronic patient dossier
Study Design
Total Participants: 1462
Study Start date:
October 01, 2022
Estimated Completion Date:
December 31, 2025
Connect with a study center
Amsterdam Universitair Medisch Centrum (AUMC) - Locatie AMC
Amsterdam, Noord-Holland
NetherlandsActive - Recruiting
Amsterdam Universitair Medisch Centrum (AUMC) - Locatie VUMC
Amsterdam, Noord-Holland
NetherlandsActive - Recruiting
Amsterdam Universitair Medisch Centrum (AUMC) - Lokatie VUMC
Amsterdam, Noord-Holland
NetherlandsSite Not Available
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