Tai Chi Versus Conventional Exercise to Improve Cognitive Performance in Older Adults With Mild Cognitive Impairment

Last updated: December 5, 2024
Sponsor: The University of Hong Kong
Overall Status: Active - Recruiting

Phase

N/A

Condition

Alzheimer's Disease

Memory Loss

Mild Cognitive Impairment

Treatment

Tai Chi

Health Education

Conventional Exercise

Clinical Study ID

NCT05540613
TC_MCI_RCT
  • Ages > 50
  • All Genders

Study Summary

This randomized controlled trial aims to evaluate the effectiveness of Tai Chi and conventional exercise on improving cognitive function in older adults with mild cognitive impairment (MCI). Participants will be randomized into three six-month programmes, namely Health Education group, Tai Chi group and Conventional Exercise group. Assessments will be conducted at baseline, after the 26-week interventions, and 26-week after the competition of the intervention.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Chinese older adults aged equal or larger than 50 years

  • Ethnic Chinese

  • MCI under criteria of Mayo Clinic, including the following i. people with subjective complaint about a decline in cognitive function. ii. totalscore in the Montreal Cognitive Assessment is equal or below the 7th percentile ofthe age- and education- corrected normative data of Hong Kong. iii. the decline incognitive function does not impair daily functioning, as revealed by getting ≥2marks in every item on the Chinese Lawton Instrumental Activities of Daily Living 4-point Scale).

Exclusion

Exclusion Criteria:

  • medical history of major chronic diseases such as cancer, stroke, cerebro- andcardio-vascular diseases, and renal disease

  • uncontrolled diabetes

  • diagnosed with dementia or using anti-dementia medication

  • diagnosed with psychiatric diseases or using psychiatric medication

  • with diseases or on medications known to severely affect cognitive performance

  • somatic condition (e.g., limb lost) that prevent participation in exercise

  • impaired mobility by chronic diseases (e.g., neurological, musculoskeletal andautoimmune diseases)

  • incapable to perform physical exercise

  • regular exercise habit (>3 times 60-min Tai Chi or moderate-intensity conventionalexercise weekly) in the past 3 months

Study Design

Total Participants: 315
Treatment Group(s): 3
Primary Treatment: Tai Chi
Phase:
Study Start date:
November 01, 2022
Estimated Completion Date:
January 31, 2026

Connect with a study center

  • The University of Hong Kong

    Hong Kong, 00
    Hong Kong

    Active - Recruiting

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