Targeting the Nine Hallmarks of Aging on DNA Methylation

Inclusion Criteria:

• Men and women of any ethnicity
• 55 years and older
• Female subjects must be post-menopausal
• Participant must be able to comply with treatment plan and laboratory tests
• Participant must be able to read, write, and speak English fluently
• Participant must have a smartphone and be able to download and use the App
• Participant must have an established primary care provider
• Participant must be willing and able to consume study supplements throughout theduration of study period

Exclusion Criteria:

• History or presence of cancer in the prior 2 years, except for non-melanoma skincancer.
• Known immune system issues or immunodeficiency disease
• History of viral illness which could be reactivated by immune downregulation
• Presence of clinically significant acute or unstable cardiovascular andcerebrovascular (stroke) disease
• Diagnosis of a transient ischemic attack in the 6 months prior to screening
• Participants infected with hepatitis C or HIV
• Presence of active infection in previous 4 weeks
• Any other illness, psychiatric disorder, alcohol or chemical dependence that in theopinion of the Clinical Investigator would render a participant unsuitable toparticipate in the study
• Unable or unwilling to provide required blood sample for testing
• Current or previous use of known prescription immunomodulating products (e.g.glucocorticoids, TNF-alpha inhibitors) in the month prior to the start of the trial.
• A known history of blood dyscrasias including coagulopathy
• Any person deemed by the Investigator as having a low likelihood of complying withstudy protocol (e.g. evidence of history of non-compliance, history of poor follow-up,multiple or complex scheduling conflicts).
• Planned surgical procedure during study period
• Participants who are actively engaged in a weight loss program or have started any newmedications during the duration of the trial that can potentially interfere with thestudy, as deemed appropriate by Principal Investigator.