A Feasibility Study to Evaluate Safety and Probable Benefit of the Eclipse XL1 System for Distraction Enterogenesis in Adult and Pediatric Patients With Short Bowel Syndrome

Inclusion Criteria:

• Subject has short bowel syndrome, defined as 50% or less of expected bowel lengthbased on subject age and/or height, and measured at the time of the subject's priorintestinal resection.

• Minimum residual bowel length of 3 cm.

• Male or female patients aged 3 mo to 65 years inclusive

• The subject, parent or legal guardian of the subject is able to read, understand,and is willing to provide informed consent.

• The subject or parent or legal guardian of the patient is able to understand therequirements of the study and is willing to bring the subject to all clinic visitsand complete all study related procedures (as determined by the investigator).

Exclusion Criteria:

• Ultra-short bowel syndrome defined as less than 3 cm of bowel length.

• Diagnosed Inflammatory bowel disease-unclassified (not Crohn's or ulcerativecolitis)

• Evidence of active or prior Crohn's disease.

• Primary intestinal failure (i.e., without loss or resection of intestinal tissue).

• Coagulopathy, as defined by INR > 1.4 or platelets < 100.

• Known immunocompromised status including, but not limited to, individuals who haveundergone organ transplantation, chemotherapy or radiotherapy within the past 12months, who have clinically significant leukopenia, who are positive for the humanimmunodeficiency virus (HIV) or whose immune status makes the subject a poorcandidate for clinical trial participation in the opinion of the Investigator.

• Subject is determined by the investigator to be unsuitable for participation in thistrial for any reason.