Natives Engaged in Alzheimers Research - 'Ike Kupuna

Last updated: July 30, 2024
Sponsor: University of Hawaii
Overall Status: Active - Recruiting

Phase

N/A

Condition

Mild Cognitive Impairment

Alzheimer's Disease

Dementia

Treatment

Ola Mau i ka Hula

Clinical Study ID

NCT05534607
'Ike Kupuna
  • Ages 50-75
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

This study will conduct a group randomized trial to test the effects of a hula-based intervention in improving vascular risk factors for ADRD and cognitive complaints and function over 12 months.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  1. self-reported Native Hawaiian or other Pacific Islander ancestry;

  2. ages 50+ but not older than 75 (optimal age range for preventing future dementia inpeople with cognitive impairment, above 75 is not likely to benefit from this studygiven their advance age);

  3. has subjective cognitive impairment (SCI) or mild cognitive impairment (MCI);

  4. have a diagnosis of hypertension, diabetes, dyslipidemia, or obesity (body-mass-index ≥ 30 kg/m2);

  5. physically able and willing to engage in moderate physical activity necessary forHula; and

  6. physician's approval to participate in moderate physical activity

Exclusion

Exclusion Criteria:

  1. currently pregnant;

  2. already actively practicing Hula at least once per week; or

  3. clinical diagnosis of ADRD (mild to severe); or

  4. current diagnosed major depressive disorder at moderate or greater stage, ormoderate or greater depression on the Center for Epidemiological Studies DepressionScale (CES-D).

Study Design

Total Participants: 192
Treatment Group(s): 1
Primary Treatment: Ola Mau i ka Hula
Phase:
Study Start date:
September 15, 2022
Estimated Completion Date:
April 30, 2027

Study Description

This study will conduct a pragmatic group-randomized trial (GRT) with NHPIs aged 50-75 years with at least 1 of 4 modifiable vascular risk factors for ADRD (hypertension, hyperglycemia, obesity, or dyslipidemia) and either SCI or MCI using a wait-list control design to test the effects of the hula-based intervention. The primary outcomes will be vascular risk factors for ADRD and subjective cognitive complaints. Secondary outcomes will include measures of cognitive performance, physical function, and mental health.

Connect with a study center

  • Kokua Kalihi Valley

    Honolulu, Hawaii 96819
    United States

    Active - Recruiting

  • Kula No Na Po'e

    Honolulu, Hawaii 96813
    United States

    Active - Recruiting

  • Hui No Ke Ola Pono

    Wailuku, Hawaii 96793
    United States

    Active - Recruiting

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