Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment

Last updated: March 24, 2025
Sponsor: Universidad de Murcia
Overall Status: Active - Recruiting

Phase

N/A

Condition

Periodontitis

Treatment

periodontal surgery

Clinical Study ID

NCT05533528
3111/2020
  • Ages > 18
  • All Genders

Study Summary

The objective of this study will be to evaluate a new protocol for the surgical treatment of periodontal disease with two novelties: to make a single incision in the midline of the interproximal area to respect the vascular supply and preserve the granulation tissue with regenerative potential.

The investigators will carry out a controlled and randomized clinical trial with a control group (n=25; modified Kirkland flap) and a test group (n=25; experimental surgical protocol: incision in the mid-interproximal area of the papilla and preservation of the granulation tissue).

Clinical parameters will be taken at the time of surgery and 12 months follow-up: bleeding on probing (BoP), clinical attachment level (CAL), residual probing depth (rPD),Probing pocket depth reduction (PPDr), recession (REC), interproximal gingival recession (iGR), width of keratinized gingiva (KT), gain of supra-alveolar clinical attachment (SUPRA-AG), early wound healing index (EHI).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Stage III or IV periodontitis, including all grades.

  • Unresolved deep pockets (probing pocket depth [PPD] >5 mm + BoP) 4 to 6 weeks afternon-surgical treatment.

  • Interproximal plaque index <35% maintained during periodontal treatment andmaintenance.

  • Adherence to periodontal maintenance appointments.

Exclusion

Exclusion Criteria:

  • Systemic disease contraindicating periodontal surgery.

  • Teeth with incorrect endodontic treatment or restoration.

  • Stage I or II periodontitis.

Study Design

Total Participants: 25
Treatment Group(s): 1
Primary Treatment: periodontal surgery
Phase:
Study Start date:
May 03, 2022
Estimated Completion Date:
February 01, 2026

Connect with a study center

  • Centro Odontologico Del Sureste Slp

    Murcia, 30007
    Spain

    Active - Recruiting

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