Speeded Anomia Treatment in Chronic Post-stroke Aphasia

Last updated: January 16, 2023
Sponsor: University of Cambridge
Overall Status: Active - Recruiting

Phase

N/A

Condition

Communication Disorders

Speech Disorders

Treatment

N/A

Clinical Study ID

NCT05512884
01/8/094
  • Ages > 18
  • All Genders

Study Summary

The main aim of the study is to investigate the effect of a novel, speeded anomia therapy (Conroy et al., 2018) in a large population of patients with chronic post-stroke aphasia. The treatment will be delivered via a web application (QuickWord).

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Native English speakers
  • Age 18 years or above
  • Stroke (any type) greater than 12 months post onset
  • No history of neurological disorders / psychiatric disorders
  • Normal or corrected-to-normal hearing & vision
  • Able to give informed consent
  • Currently not receiving Speech & Language therapy
  • Minimal repetition skills (>40% on an immediate word repetition test)
  • Evidence of naming difficulties (<90% in Boston Naming Test - Goodglass et al., 1983)

Exclusion

Exclusion Criteria:

  • Non-native English speakers
  • Less than 18 years old
  • Stroke less than 12 months post onset
  • History of neurological disorders / psychiatric disorders
  • Uncorrected hearing & vision
  • Unable to give informed consent
  • Currently receiving Speech & Language therapy
  • Insufficient repetition skills (<40% on an immediate word repetition test)
  • Good naming performance (>90% in Boston Naming Test - Goodglass et al., 1983)

Study Design

Total Participants: 100
Study Start date:
January 15, 2023
Estimated Completion Date:
September 01, 2023

Study Description

The main aim is to test the clinical efficacy of a novel, web based, rehabilitation approach to aphasic word-finding difficulties (QuickWord). In an initial development and case-series evaluation, Conroy et al (2018, Brain) found that training for both speed as well as accuracy of naming generated much better outcomes to picture naming accuracy and also augmented the carry-over to connected speech production.

This is a randomised, crossover, clinical trial of QuickWord in a group of aphasic patients in the chronic post-stroke period. The comparison will be standard care. The main outcome measures are clinically relevant improvement in naming to confrontation, and spontaneous use of the target vocabulary in a connected speech sample (detailed picture description). Secondary outcome includes measured use of the vocabulary in a story-telling, connected speech assessment (retelling of the Cinderella story).

Connect with a study center

  • MRC Cognition & Brain Sciences Unit

    Cambridge, CB2 7EF
    United Kingdom

    Active - Recruiting

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